Nifedipine and thrombocytopenia.

Nifedipine–pyrazine (2/1)

In the title compound, 2C(17)H(18)N(2)O(6)·C(4)H(4)N(2) [systematic name: 3,5-dimethyl 2,6-dimethyl-4-(2-nitro-phen-yl)-1,4-di-hydro-pyridine-3,5-dicarboxyl-ate-pyrazine (2/1)], the complete pyrazine molecule is generated by crystallographic inversion symmetry. The center of the pyrazine ring lies on an inversion center. The nifedipine mol-ecules are linked into chains along the c axis through ...

Hyperglycaemic effect of nifedipine.

histotoxic symptoms may be due to these, but the exact mechanism of action of thiocyanates is not known.4 Thiocyanate intoxication with blood concentrations above 200 mg/l may be rapidly corrected by haemodialysis, which reportedly removes several grams of the drug.5 We tried peritoneal dialysis but in the absence of clearance studies, which we could not do, we cannot comment on the procedure f...

Nifedipine GITS Package Insert

Cilazapril, Atenolol, Nifedipine

A multicenter, randomized double-blind study of 6 months' duration was performed in 540 patients (average age 54 years, 57% male) with mild-to-moderate essential hypertension to determine the relative effects on quality of life of cilazapril, atenolol, and nifedipine retard. Quality of life was assessed by using both a self-administered and an interviewer-administered questionnaire; the assessm...

Nifedipine for tocolysis.

The release of the new WHO recommendations (October, 2015) for preterm birth interventions is welcome. With regard to the place of tocolysis, the guidelines present a balanced view of the current uncertainties and indicate a preference for nifedipine as the drug of choice when tocolysis is considered, while emphasising the need for further research. However, an important issue in the availabili...